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Antibodies

DYNLL1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-11159-20UL
60 ul
£183.00
E-AB-11159-60UL
120 ul
£272.00
E-AB-11159-120UL
200 ul
£420.00
E-AB-11159-200UL
About this Product
SKU:
E-AB-11159
Additional Names:
8 kDa dynein light chain,8kDLC,Cytoplasmic dynein light polypeptide,DLC1,DLC8,DNCL1,DNCLC1,DYL1,Dynein,Dynein light chain 1,Dynein light chain 1 cytoplasmic,Dynein light chain LC8 type 1,Dynein light chain LC8-type 1,cytoplasmic,light chain 1
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.
Host:
Rabbit
Immunogen:
Recombinant protein of human DYNLL1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody