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Antibodies

CYP17A1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-11124-20UL
60 ul
£183.00
E-AB-11124-60UL
120 ul
£272.00
E-AB-11124-120UL
200 ul
£420.00
E-AB-11124-200UL
About this Product
SKU:
E-AB-11124
Additional Names:
20 lyase,CP17A,CPT7,CYP17,CYP17A1,CYPXVII,Cytochrom,Cytochrome P450 17A1,Cytochrome P450 family 17,Cytochrome P450 family 17 subfamily A polypeptide 1,Cytochrome p450 XVIIA1,Cytochrome p450 subfamily XVII (steroid 17 alpha hydroxylase) adrenal hyperplasia
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.7 mg/ml
Extra Details:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
Host:
Rabbit
Immunogen:
Recombinant protein of human CYP17A1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody