CRK Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-11105-20UL
60 ul
£183.00
E-AB-11105-60UL
120 ul
£272.00
E-AB-11105-120UL
200 ul
£420.00
E-AB-11105-200UL
About this Product
- SKU:
- E-AB-11105
- Additional Names:
- Adapter molecule crk;Avian sarcoma virus CT10 (v crk) oncogene homolog;CRK;CRK isoform 2;CRK isoform II;CRKII;FLJ38130;OTTHUMP00000115366;OTTHUMP00000198330;Proto oncogene C crk;Proto-oncogene C-crk;p38;v crk avian sarcoma virus CT10 oncogene homolog
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.4 mg/ml
- Extra Details:
- This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human CRK
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-crk_polyclonal_antibody-e_ab_11105
