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Antibodies

CCDC106 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-11038-20UL
60 ul
£183.00
E-AB-11038-60UL
120 ul
£272.00
E-AB-11038-120UL
200 ul
£420.00
E-AB-11038-200UL
About this Product
SKU:
E-AB-11038
Additional Names:
CC106,Ccdc106,Coiled-coil domain-containing protein 106,HSU79303,Protein predicted by clone 23882,ZNF581
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.3 mg/ml
Extra Details:
The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.
Host:
Rabbit
Immunogen:
Recombinant protein of human CCDC106
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody