BABAM2 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-11008-20UL
60 ul
£183.00
E-AB-11008-60UL
120 ul
£272.00
E-AB-11008-120UL
200 ul
£420.00
E-AB-11008-200UL
About this Product
- SKU:
- E-AB-11008
- Additional Names:
- 6030405P19Rik,AI429776,B830038C02Rik,BRCA1 A complex subunit BRE,BRCA1-A complex subunit BRE,BRCA1/BR,Brain and reproductive organ expressed (TNFRSF1A modulator),Brain and reproductive organ-expressed protein,brain and reproductive organ expressed protein
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Brain and reproductive organ-expressed protein (BRE) is a 415 amino acid protein which binds to the intracellular juxtamembrane domain of the death receptor, tumor necrosis factor receptor 1 (TNF-R1). BRE also binds to the death receptor, FAS. BRE downregulates TNFa-induced activation of NFkB and may play a role in homeostasis or cellular differentiation in cells of epithelial, neural and germ line origins. It inhibits components of the death-inducing signaling complexes that are necessary for activation of the mitochondria, thereby mediating apoptosis. BRE is strongly expressed in the adrenal cortex, medulla, testis and pancreas, and is weakly expressed in the thymus, thyroid, stomach and small intestine.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human BRE
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-babam2_polyclonal_antibody-e_ab_11008
