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Antibodies

AURKAIP1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-10976-20UL
60 ul
£183.00
E-AB-10976-60UL
120 ul
£272.00
E-AB-10976-120UL
200 ul
£420.00
E-AB-10976-200UL
About this Product
SKU:
E-AB-10976
Additional Names:
28S ribosomal protein S38,AIP,AKIP,AURKA interacting protein,AURKA-interacting protein,AURKAIP 1,Aurkaip1,Aurora A kinase interacting protein,Aurora kinase A interacting protein 1,Aurora kinase A-interacting protein,FLJ20608,MRP-S38,mitochondrial
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.2 mg/ml
Extra Details:
AKIP (AURKA-interacting protein), also known as AURKAIP1 (aurora kinase A interacting protein 1) or AIP, is a 199 amino acid protein that localizes to the nucleus and is ubiquitously expressed, with highest levels present in testis, heart and skeletal muscle. Interacting specifically with ARK-1 (aurora kinase 1), AKIP functions to induce the proteasomal-dependent degradation of ARK-1, thereby acting as a negative regulator of ARK-1 activity. AKIP is encoded by a gene which maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Host:
Rabbit
Immunogen:
Recombinant protein of human AURKAIP1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody