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Antibodies

IKZF3 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-10975-20UL
60 ul
£183.00
E-AB-10975-60UL
120 ul
£272.00
E-AB-10975-120UL
200 ul
£420.00
E-AB-10975-200UL
About this Product
SKU:
E-AB-10975
Additional Names:
AIO;Aiolos;IKAROS family zinc finger 3;IKAROS family zinc finger 3 (Aiolos);IKZF 3;IKZF3;Ikaros family zinc finger protein 3;Zinc finger pr;Zinc finger protein Aiolos;Zinc finger protein subfamily 1A 3 (Aiolos);zinc finger DNA binding protein Aiolos
Application:
Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.7 mg/ml
Extra Details:
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.
Host:
Rabbit
Immunogen:
Recombinant protein of human IKZF3
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody