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Antibodies

CERK Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-10955-20UL
60 ul
£183.00
E-AB-10955-60UL
120 ul
£272.00
E-AB-10955-120UL
200 ul
£420.00
E-AB-10955-200UL
About this Product
SKU:
E-AB-10955
Additional Names:
Acylsphingosine kinase;CERK1;Ceramide kinase;Cerk;KIAA1646;LK4;Lipid kinase 4;Lipid kinase LK4;dA59H18.2;dA59H18.3;hCERK
Application:
Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.3 mg/ml
Extra Details:
CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.
Host:
Rabbit
Immunogen:
Recombinant protein of human CERK
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody