USP2 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-10878-20UL
60 ul
£183.00
E-AB-10878-60UL
120 ul
£272.00
E-AB-10878-120UL
200 ul
£420.00
E-AB-10878-200UL
About this Product
- SKU:
- E-AB-10878
- Additional Names:
- 41 kDa ubiquitin specific protease,41 kDa ubiquitin-specific protease,Deubiquitinating enzyme 2,Ubiquit,Ubiquitin carboxyl terminal hydrolase 2,Ubiquitin carboxyl-terminal hydrolase 2,Ubiquitin specific processing protease 2,ubiquitin specific peptidase 2
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.3 mg/ml
- Extra Details:
- This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human USP2
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-usp2_polyclonal_antibody-e_ab_10878
