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Antibodies

SETD2 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-10851-20UL
60 ul
£183.00
E-AB-10851-60UL
120 ul
£272.00
E-AB-10851-120UL
200 ul
£420.00
E-AB-10851-200UL
About this Product
SKU:
E-AB-10851
Additional Names:
EC 2.1.1.43,FLJ16420,FLJ22472,FLJ23184,FLJ45883,HBP231,HIF 1,HIF-1,HIF1,HIP-1,HSPC069,Histone lysine N methyltransferase SETD2,Histone-lysine N-methyltransferase SETD2,Huntingtin intera,Huntingtin interacting protein,Huntingtin interacting protein 1,hSET2
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.2 mg/ml
Extra Details:
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
Host:
Rabbit
Immunogen:
Recombinant protein of human SETD2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody