ARC Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-10826-20UL
60 ul
£183.00
E-AB-10826-60UL
120 ul
£272.00
E-AB-10826-120UL
200 ul
£420.00
E-AB-10826-200UL
About this Product
- SKU:
- E-AB-10826
- Additional Names:
- ARC,ARC/ARG3.1,Activity-regulated cytoskeleton-associated protein,Activity-regulated gene 3.1 protein homolog,Arc,Arg3.1,activity regulated cytoskeleton associated protein,activity regulated gene 3.1 protein homolog
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Arc (for activity-regulated cytoskeleton-associated protein) is a growth factor and immediate early gene that is enriched in brain. Arc mRNA and protein levels are induced by neuronal activity, which is necessary to stimulate neuroplasticity, indicating a potential role for Arc in activity-dependent changes in dendrite function. Arc expression has been detected in neuronal cell bodies and dendrites in the hippocampus, amygdala, hypothalamus, striatum and cortex. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human ARC
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-arc_polyclonal_antibody-e_ab_10826
