ALKBH1 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-10699-20UL
60 ul
£183.00
E-AB-10699-60UL
120 ul
£272.00
E-AB-10699-120UL
200 ul
£420.00
E-AB-10699-200UL
About this Product
- SKU:
- E-AB-10699
- Additional Names:
- ABH,ABH1,ALKB1,ALKBH,ALKBH1,AlkB,Alkylated DNA repair protein alkB homolog 1,Alkylation repair,Alkylation repair homolog 1,Alpha-ketoglutarate-dependent dioxyge,alkB,alkB homolog,alkB homolog 1 histone H2A dioxygenase,alkylation repair homolog 1 (E. coli)
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.3 mg/ml
- Extra Details:
- This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human ALKBH1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-alkbh1_polyclonal_antibody-e_ab_10699
