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Antibodies

PLAUR Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-10547-20UL
60 ul
£183.00
E-AB-10547-60UL
120 ul
£272.00
E-AB-10547-120UL
200 ul
£420.00
E-AB-10547-200UL
About this Product
SKU:
E-AB-10547
Additional Names:
CD 87,CD87,CD87 antigen,MO 3,MO3,Monocyte activation antigen Mo3,PLAUR,Plasminogen activator receptor urokinase,Plasminogen activator urokinase receptor,U PAR,U-PAR,UPA receptor,u plasminogen activator receptor,u-plasminogen activator receptor form 2,uPAR
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.4 mg/ml
Extra Details:
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Host:
Rabbit
Immunogen:
Recombinant protein of human PLAUR
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody