CDKN2AIP Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-10510-20UL
60 ul
£183.00
E-AB-10510-60UL
120 ul
£272.00
E-AB-10510-120UL
200 ul
£420.00
E-AB-10510-200UL
About this Product
- SKU:
- E-AB-10510
- Additional Names:
- CARF,CDKN2A interacting protein,CDKN2A-interacting protein,Calcium response factor,Cdkn2aip,Collaborator of ARF,FLJ20036,collaborates/cooperates with ARF (alternate reading frame) protein
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.3 mg/ml
- Extra Details:
- CDKN2AIP (CDKN2A-interacting protein), also known as CARF, is a 580 amino acid protein that activates p53 via p14 ARF (alternate reading frame)-dependent and independent pathways. CDKN2AIP-dependent activation of p53, a protein that up-regulates growth arrest and apoptosis-related genes in response to stress signals, leads to an enhancement of p53 function. Expression levels of CDKN2AIP and p53 show an inverse relationship that is caused by a negative-feedback control via a proteasome-mediated degradation pathway. CDKN2AIP is expressed ubiquitously across tissue samples and, along with p14 ARF, is localized to the perinucleolar region within the nucleus.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human CDKN2AIP
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cdkn2aip_polyclonal_antibody-e_ab_10510
