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Antibodies

MUTYH Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-10477-20UL
60 ul
£183.00
E-AB-10477-60UL
120 ul
£272.00
E-AB-10477-120UL
200 ul
£420.00
E-AB-10477-200UL
About this Product
SKU:
E-AB-10477
Additional Names:
A/G specific adenine DNA glycosylase,A/G-specific adenine DNA glycosylase,Adenine DNA glycosylase,CYP2C,E. coli,MGC4416,MUTYH,MYH,MutY,MutY (E. coli) homolog,MutY homolog,MutY homolog (E. coli),Mutyh,hMYH,homolog of,rMYH
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.3 mg/ml
Extra Details:
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant protein of human MUTYH
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody