MMP14 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-10461-20UL
60 ul
£183.00
E-AB-10461-60UL
120 ul
£272.00
E-AB-10461-120UL
200 ul
£420.00
E-AB-10461-200UL
About this Product
- SKU:
- E-AB-10461
- Additional Names:
- Matrix metallopeptidase 14 (membrane inserted),Matrix metalloproteinase 14,Matrix metalloproteinase-14,Membrane type 1 matrix metalloproteinase,Membrane type 1 metalloprotease,Membrane type matrix metalloproteinase 1,Membrane-type matrix metalloproteinase
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.4 mg/ml
- Extra Details:
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human MMP14
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-mmp14_polyclonal_antibody-e_ab_10461
