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Antibodies

BAIAP2 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-10414-20UL
60 ul
£183.00
E-AB-10414-60UL
120 ul
£272.00
E-AB-10414-120UL
200 ul
£420.00
E-AB-10414-200UL
About this Product
SKU:
E-AB-10414
Additional Names:
BAI-associated protein 2,BAI1 associated protein 2,BAI1-associated protein 2,BAIAP 2,BAIP2,BAP2,Baiap2,Brain-specific angiogenesis inhibitor 1-associated protein 2,FLAF3,Fas ligand-associated factor 3,Insulin receptor substr,Insulin receptor substrate p53
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.2 mg/ml
Extra Details:
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms
Host:
Rabbit
Immunogen:
Recombinant protein of human BAIAP2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody