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Antibodies

ITGB3BP Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-10402-20UL
60 ul
£183.00
E-AB-10402-60UL
120 ul
£272.00
E-AB-10402-120UL
200 ul
£420.00
E-AB-10402-200UL
About this Product
SKU:
E-AB-10402
Additional Names:
Beta 3 endonexin,Beta-3,Beta3 endonexin,Beta3 endonexin long form,CENP R,CENPR,Centromere protein R,HSU37139,Integrin beta 3 binding protein,Integrin beta 3 binding protein (beta3-endonexin),NRIF 3,NRIF3,Nuclear receptor interacting factor,endonexin
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.7 mg/ml
Extra Details:
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Recombinant protein of human ITGB3BP
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody