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Antibodies

EDN3 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-10312-20UL
60 ul
£183.00
E-AB-10312-60UL
120 ul
£272.00
E-AB-10312-120UL
200 ul
£420.00
E-AB-10312-200UL
About this Product
SKU:
E-AB-10312
Additional Names:
EDN3;ET 3;ET-3;Endothelin-3;PPET3;Preproendothelin 3;Preproendothelin-3
Application:
Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells.
Host:
Rabbit
Immunogen:
Recombinant protein of human EDN3
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody