ARRB1 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-10174-20UL
60 ul
£183.00
E-AB-10174-60UL
120 ul
£272.00
E-AB-10174-120UL
200 ul
£420.00
E-AB-10174-200UL
About this Product
- SKU:
- E-AB-10174
- Additional Names:
- ARB1,ARR1,ARRB1,Arrestin 2,Arrestin beta 1,Arrestin beta-1,Beta-arrestin-1
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.4 mg/ml
- Extra Details:
- Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human ARRB1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-arrb1_polyclonal_antibody-e_ab_10174
