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Antibodies

AMACR Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-10127-20UL
60 ul
£183.00
E-AB-10127-60UL
120 ul
£272.00
E-AB-10127-120UL
200 ul
£420.00
E-AB-10127-200UL
About this Product
SKU:
E-AB-10127
Additional Names:
2 methylacyl CoA racemase,2-methylacyl-CoA racemase,AMACR,AMACRD,Alpha methylacyl CoA racemase,Alpha-methylacyl-CoA racemase,Amacr,CBAS4,EC 5.1.99.4,Macr1,RACE,RM
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.1 mg/ml
Extra Details:
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Host:
Rabbit
Immunogen:
Recombinant protein of human AMACR
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody