AIFM1 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-10123-20UL
60 ul
£183.00
E-AB-10123-60UL
120 ul
£272.00
E-AB-10123-120UL
200 ul
£420.00
E-AB-10123-200UL
About this Product
- SKU:
- E-AB-10123
- Additional Names:
- 1,AIFM1,Apoptosis inducing factor,Apoptosis inducing factor 1,Apoptosis-inducing factor 1,CMTX4,COWCK,COXPD6,Harlequin,Hq,MGC111425,MGC5706,Neuropathy,axonal motor-s,mAIF,mitochondrial,mitochondrion associated
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells.Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation.In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy.Alternative splicing results in multiple transcript variants.A related pseudogene has been identified on chromosome 10.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human AIFM1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-aifm1_polyclonal_antibody-e_ab_10123
