TLR3 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-10066-20UL
60 ul
£183.00
E-AB-10066-60UL
120 ul
£272.00
E-AB-10066-120UL
200 ul
£420.00
E-AB-10066-200UL
About this Product
- SKU:
- E-AB-10066
- Additional Names:
- CD283;CD283 antigen;IIAE2;TLR 3;TLR3;Tlr3;Toll Like Receptor 3;Toll-like receptor 3
- Application:
- Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.3 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human TLR3
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-tlr3_polyclonal_antibody-e_ab_10066
