STAT6 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-10059-20UL
60 ul
£183.00
E-AB-10059-60UL
120 ul
£272.00
E-AB-10059-120UL
200 ul
£420.00
E-AB-10059-200UL
About this Product
- SKU:
- E-AB-10059
- Additional Names:
- 12S1644;D12S1644;IL 4 STAT;IL-4 Stat;IL4 STAT;Interleukin 4 Induced;Interleukin 4 Induced Transcription Factor IL4 STAT;Signal Tran;Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced;Signal transducer and activator of transcription 6
- Application:
- Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human STAT6
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-stat6_polyclonal_antibody-e_ab_10059
