CASP4 Polyclonal Antibody
Product Sizes
25 ul
£134.00
D-AB-10447L-25UL
100 ul
£291.00
D-AB-10447L-100UL
About this Product
- SKU:
- D-AB-10447L
- Additional Names:
- Apoptotic cysteine protease Mih1/TX,CASP-4,CASP4,Caspase 4 apoptosis related cysteine peptidase,Caspase-4 subunit 2,Caspase4,ICE(rel)-II,ICE(rel)II,ICEREL II,ICH2,Mih1/TX,Protease ICH-2,Protease TX,TX
- Application:
- Immunofluorescence, Immunohistochemistry
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the cysteine proteases that plays important roles in apoptosis,cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is ",caspase 4,apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CASP4 protein expressed by E.coli
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-casp4_polyclonal_antibody-d_ab_10447l
