SFTPD/SP-D Polyclonal Antibody
Product Sizes
25 ul
£134.00
D-AB-10441L-25UL
100 ul
£291.00
D-AB-10441L-100UL
About this Product
- SKU:
- D-AB-10441L
- Additional Names:
- Lung surfactant protein D;PSP-D;Pulmonary surfactant-associated protein D;SP-D;Sftp4;Sftpd
- Application:
- Western Blot
- Buffer:
- PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Pulmonary surfactant-associated protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Mouse SP-D cDNA encodes a 19 aa signal sequence and a 355 aa mature region with a 25 aa N-terminal linking-region,a 177 aa hydroxyproline and hydroxylysine collagen-like domain,a 46 aa coiled-coil segment,and a 106 aa,C-terminal collectin-like C-type lectin domain . SP-D is found in serum,plasma,broncho-alveolar lavage (BAL) fluid,and amniotic fluid. It also binds SIRP alpha and the calreticulin/CD91 complex on macrophages. SP-D contributes to the lung's defense against inhaled microorganisms,organic antigens and toxins. It Interacts with compounds such as bacterial lipopolysaccharides,oligosaccharides and fatty acids and modulates leukocyte action in immune response. It may participate in the extracellular reorganization or turnover of pulmonary surfactant. It binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
- Host:
- Rabbit
- Immunogen:
- Recombinant Mouse SFTPD/SP-D protein expressed by Mammalian
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:sp_d_polyclonal_antibody-d_ab_10441l
