CTSB Polyclonal Antibody
Product Sizes
25 ul
£134.00
D-AB-10435L-25UL
100 ul
£291.00
D-AB-10435L-100UL
About this Product
- SKU:
- D-AB-10435L
- Additional Names:
- APP secretase;APPS;Amyloid precursor protein secretase;CATB;CPSB;CTSB;Cathepsin B heavy chain;Cathepsin B1;CathepsinB;OTTHU;OTTHUMP00000116009;OTTHUMP00000229510;OTTHUMP00000229511;OTTHUMP00000229512;OTTHUMP00000229514;OTTHUMP00000229515;cysteine protease
- Application:
- Western Blot
- Buffer:
- PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains,both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease,the most common cause of dementia. Overexpression of the encoded protein,which is a member of the peptidase C1 family,has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CTSB protein expressed by Mammalian
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-ctsb_polyclonal_antibody-d_ab_10435l
