CDNF Polyclonal Antibody
Product Sizes
25 ul
£134.00
D-AB-10383L-25UL
100 ul
£291.00
D-AB-10383L-100UL
About this Product
- SKU:
- D-AB-10383L
- Additional Names:
- ARMET-like protein 1,ARMETL1,CDNF,Cerebral dopamine neurotrophic factor,Conserved dopamine neurotrophic factor
- Application:
- Western Blot
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Cerebral Dopamine Neurotrophic Factor (CDNF),also known as ARMETL1 (ARMET-like protein 1),is a secreted protein with eight conserved cysteine residues,predicting a unique protein fold and defining a new,evolutionarily conserved protein family. CDNF is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons comparable to that of glial cell line-derived neurotrophic factor (GDNF). CDNF/ARMETL1 is a evolutionary conserved protein which can protect and restore the function of dopaminergic neurons in the rat model of Parkinson's disease,suggesting that CDNF might be beneficial for the treatment of Parkinson's disease. CDNF is widely expressed in neurons in several brain regions including cerebral cortex,hippocampus,substantia nigra,striatum and cerebellum. Human CDNF is glycosylated and secreted from transiently transfected cells. CDNF promotes the survival,growth,and function of dopamine-specific neurons and is expressed in brain regions that undergo cocaine-induced neuroplasticity.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CDNF protein expressed by Mammalian
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cdnf_polyclonal_antibody-d_ab_10383l
