GSTM1 Polyclonal Antibody
Product Sizes
25 ul
£134.00
D-AB-10378L-25UL
100 ul
£291.00
D-AB-10378L-100UL
About this Product
- SKU:
- D-AB-10378L
- Additional Names:
- EC:2.5.1.18,GST 1-1,GST class-mu 1,Glutathione S-transferase GT8.7,Glutathione S-transferase Mu 1,Gstm1,pmGT10
- Application:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present,eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha,kappa,mu,omega,pi,sigma,theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds,including carcinogens,therapeutic drugs,environmental toxins and products of oxidative stress,by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers,likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant Mouse GSTM1 protein expressed by E.coli
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-gstm1_polyclonal_antibody-d_ab_10378l
