SDHB Polyclonal Antibody
Product Sizes
25 ul
£134.00
D-AB-10362L-25UL
100 ul
£291.00
D-AB-10362L-100UL
About this Product
- SKU:
- D-AB-10362L
- Additional Names:
- Ip, DHSB, Iron sulfur subunit, Iron sulfur subunit of complex II, Iron-sulfur subunit of complex II, PGL 4, PGL4, SDH, SDH 1, SDH1, SDH2, SDHIP, SdhB, Succinate dehydrogenase [ubiquinone] iron sulfur protein mitocho, homolog of, mitochondrial,CWS2
- Application:
- Immunohistochemistry
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human SDHB protein expressed by E.coli
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-sdhb_polyclonal_antibody-d_ab_10362l
