CD59 Polyclonal Antibody
Product Sizes
25 ul
£134.00
D-AB-10258L-25UL
100 ul
£291.00
D-AB-10258L-100UL
About this Product
- SKU:
- D-AB-10258L
- Additional Names:
- 16.3A5;1F5;1F5 antigen;20 kDa homologous restriction factor;CD 59;CD59;CD59 antigen;CD59 antigen complement regulatory protein ;CD59 antigen p18 20;CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5;CD_antigen=CD59;EJ16;EJ30;EL32 and
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CD59 protein expressed by E.coli
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cd59_polyclonal_antibody-d_ab_10258l
