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Antibodies

JNK2 Polyclonal Antibody

Product Sizes
25 ul
£134.00
D-AB-10207L-25UL
100 ul
£291.00
D-AB-10207L-100UL
About this Product
SKU:
D-AB-10207L
Additional Names:
MAPK,PRKM,JNK,MAPK9,JNK-55,JNK2,JNK2A,JNK2ALPHA,JNK2B,JNK2BETA,PRKM9,SAPK,SAPK1a,p54a,p54aSAPK,c Jun kinase 2,C Jun N terminal kinase 2,c-Jun N-terminal kinase 2,JNK 55,JNK2 alpha,JNK2 beta,Jun kinase,MAP kinase 9,MAPK 9,Mitogen activated protein kinase 9,mitogen-activated,Mitogen-activated protein kinase 9,MK09,Protein kinase,SAPK alpha,Stress activated protein kinase 1a,Stress-activated protein kinase JNK2
Application:
Western Blot
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Host:
Rabbit
Immunogen:
Recombinant Human MAPK9 protein expressed by E.coli
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody