E-Cadherin Polyclonal Antibody
Product Sizes
25 ul
£134.00
D-AB-10198L-25UL
100 ul
£291.00
D-AB-10198L-100UL
About this Product
- SKU:
- D-AB-10198L
- Additional Names:
- Arc 1,CADH1,CAM 120/80,CD 324,CD324,CD324 antigen,CDHE,Cadherin 1,Cadherin1,E-Cad/CTF3,E-cadherin,ECAD,Epithelial cadherin,LCAM,Liver cell adhesion molecule,UVO,Uvomorulin,cadherin 1 type 1 E-cadherin,cdh1,epithelial calcium dependant adhesion protein
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats,a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric,breast,colorectal,thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation,invasion,and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CDH1 protein expressed by E.coli
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-e_cadherin_polyclonal_antibody-d_ab_10198l
