CD22 Polyclonal Antibody
Product Sizes
25 ul
£134.00
D-AB-10188L-25UL
100 ul
£291.00
D-AB-10188L-100UL
About this Product
- SKU:
- D-AB-10188L
- Additional Names:
- B lymphocyte cell adhesion molecule; BL CAM; CD 22; CD22 antigen; CD22 molecule; Lectin 2; Leu14; Lyb8; MGC130020; SIGLEC 2; T cell surface antigen Leu 14; sialic acid binding Ig like lectin 2;B cell receptor CD22 precursor
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- CD22,also known as Siglec-2 (sialic acid binding Ig-like lectin 2) or BL-CAM (B-lymphocyte cell adhesion molecule),is a 130-140 kDa,B-cell restricted,type I transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. The expression of CD22 is developmentally regulated. It is expressed at low levels in the cytoplasm of pro-B and pre-B cells and present on the cell surface only at mature stages of B-cell differentiation. Cell surface expression is lost during terminal differentiation into plasma cell and after B-cell activation. CD22 is an inhibitory receptor for B-cell receptor (BCR) signalling,preferentially binds to alpha-2,6-linked sialic acid and mediates B-cell B-cell interactions. It plays a crucial role in activation and differentiation of the B-cell.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CD22 protein expressed by E.coli
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cd22_polyclonal_antibody-d_ab_10188l
