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Antibodies

HSPA5 Polyclonal Antibody

Product Sizes
25 ul
£134.00
D-AB-10170L-25UL
100 ul
£291.00
D-AB-10170L-100UL
About this Product
SKU:
D-AB-10170L
Additional Names:
78 kDa glucose-regulated protein;BIP;Binding-immunoglobulin protein;Endoplasmic reticulum chaperone BiP;GRP;GRP-78;GRP78;HEL-S-89n;HSP70 family protein;HSP70 family protein 5;HSPA;HSPA5;Heat shock protein family A member;Immunoglobulin heavy chai;MIF;MIF2
Application:
Western Blot
Buffer:
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen.Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate .Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR).In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to disrupt the dimerization of ERN1/IRE1, thereby inactivating ERN1/IRE1.
Host:
Rabbit
Immunogen:
Recombinant Human HSPA5 protein expressed by E.coli
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody