AMPK alpha2 Polyclonal Antibody
Product Sizes
25 ul
£134.00
D-AB-10161L-25UL
100 ul
£291.00
D-AB-10161L-100UL
About this Product
- SKU:
- D-AB-10161L
- Additional Names:
- 5'-AMP-activated protein kinase catalytic subunit alpha-2,AAPK2,ACACA kinase,AMPK alpha 2 chain,AMPK subunit alpha-2,AMPK2,AMPKa2,AMPKalpha2,Acetyl-CoA carboxylase kinase,HMGCR kinase,Hydroxymethylglutaryl-CoA reductase kinase,PRKAA,PRKAA2,Protein kinase
- Application:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
- Host:
- Rabbit
- Immunogen:
- Recombinant Rat Ampk2 protein expressed by E.coli
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-ampk_alpha2_polyclonal_antibody-d_ab_10161l
