Recombinant Histone H4 (Mono Methyl Lys12) Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN302114L-50UL
100 ul
£402.00
AN302114L-100UL
About this Product
- SKU:
- AN302114L
- Additional Names:
- H4F;methyl histone H;methylated histone H;HIST2H;HIST1H;HISTH4H;histone H;HIST2H4B;H4/o;histone H4;HIST1H4A;FO108;H4/p;HIST1H4;Hist4h4;HISTH4H4;methyl histone H4;methylated histone H4;H4/A;H4FA;H4/I;H4FI;HIST1H4B;H4/G;H4FG;HIST1H4C;H4/B;H4FB;HIST1H4D;H4/J;H4FJ;HIST1H4E;H4/C;H4FC;HIST1H4F;H4/H;H4FH;HIST1H4H;H4/M;H4FM;HIST1H4I;H4/E;H4FE;H4/D;H4FD;HIST1H4K;H4/K;H4FK;HIST1H4L;H4/N;H4F2;H4FN;HIST2H4;HIST2H4A;H4;H4C1;H4C2;H4C3;H4C4;H4C5;H4C6;H4C8;H4C9;H4C11;H4C12;H4C13;H4C14;H4C15;H4-16;A;I;H4B;H4J;H4H;H4M;H4E;HIST1H4J;H4D;H4C;H4/p;histone H4;HIST1H4B H4/I
- Application:
- ChIP, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A838
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The amino-terminal tails of core histones undergo lysine methylation in multiple sites, termed as "histone code" or "epigenetic code". Lysine methylation in core histones is a major determinant for the formation of active and inactive regions of the genome and therefore plays vital roles in multiple cellular events. In most species, lysine methylation occurs primarily on histones H3 (Lys4, 9, 27, 36, 79) and H4 (Lys5, 8, 12, 20) and has been implicated in both transcriptional activation and silencing. Methylation in histones modulated by specific histone methyltransferases (HMTs) and histone demethylases (HDMs) is impaired in the pathologies of cancer and other diseases and therefore, enzymes regulating histone lysine methylation have become promising targets for anti-cancer drugs.
- Host:
- Rabbit
- Immunogen:
- Monomethylated human histone H4 (Lys12) peptide
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_histone_h4_(mono_methyl_lys12)_monoclonal_antibody-an302114l
