Recombinant NELF-B Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN302066L-50UL
100 ul
£402.00
AN302066L-100UL
About this Product
- SKU:
- AN302066L
- Additional Names:
- KIAA;COBRA;NELFB;COBRA1;NELF-B;KIAA1182
- Application:
- Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A786
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- NELF-B is an essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNApolymerase II. The NELF complex causes transcriptional pausing and is counteracted by the P-TEFb kinase complex. It may be able toinduce chromatin unfolding. NELF-B is a modulator of ligand dependent and independent expression of estrogen receptor-A Alpha target genes.NELF-B expression is reduced in metastatic and recurrent breast cancer, suggesting that low levels of NELF-B in breast cancers may serveas an indicator for poor prognosis.
- Host:
- Rabbit
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_nelf_b_monoclonal_antibody-an302066l
