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Antibodies

Recombinant MCM7 Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN302062L-50UL
100 ul
£402.00
AN302062L-100UL
About this Product
SKU:
AN302062L
Additional Names:
CDC;PNAS;P1CDC;PPP1R;P1.1-MCM;MCM;MCM7;CDC47;MCM2;P1.1-MCM3;P1CDC47;P85MCM;PNAS146;PPP1R104;formerly;homolog of;regulatory subunit 104;S. cerevisiae;CDABP0042;CDC 47;CDC47 homolog;DNA replication licensing factor MCM7;Homolog of S. cerevisiae Cdc47;MCM 2;MCM 7;MCM7 minichromosome maintenance deficient 7;MCM7_HUMAN;Minichromosome maintainence;Minichromosome Maintainence 7;Minichromosome maintenance complex component 7;Minichromosome maintenance deficient 7;Minichromosome maintenance protein 7;P1.1 MCM3;PNAS 146;Protein phosphatase 1
Application:
Immunofluorescence, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A782
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Host:
Rabbit
Immunogen:
Peptide. This information is proprietary to PTMab.
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies