Recombinant EGR2 Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN302056L-50UL
100 ul
£402.00
AN302056L-100UL
About this Product
- SKU:
- AN302056L
- Additional Names:
- EGR;KROX;EGR2;AT591;CMT1D;CMT4E;KROX20;DKFZp686J1957;Drosophila;E3 SUMO-protein ligase EGR2;early growth response 2;Early growth response protein 2;EGR-2;FLJ14547;homolog (early growth response-2);KROX 20 Drosophila homolog;Krox 20 homolog Drosophila;KROX-20;Krox20 protein;Zinc finger protein Krox-20
- Application:
- Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A776
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- EGR2 is also named as KROX20, belongs to the EGR C2H2-type zinc-finger protein family. As a zinc finger transcription factor, it is observed in both the somata and dendrites of central neurons. EGR2 plays an important role in the transient formation of hindbrain developmental compartments or rhombomeres and is also an important factor in peripheral myelination, maintenance of synaptic plasticity and long-term potentiation. EGR2 expression is induced downstream of TCR signaling in NKT precursors and EGR2 is directly connected with the key molecular checkpoints defining NKT lineage commitment and stage progression, suggesting that EGR2 not only induces the early lineage-defining transcription factor PLZF, but also controls the downstream expression of the IL-2RB Beta chain. EGR2 is regulated by both soluble and membrane-bound neuregulins and its concentration is partially modulated by calcium-dependent events. EGR2/Krox20 is also required for induction of Pmp22, and is nuclear-localized.
- Host:
- Rabbit
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_egr2_monoclonal_antibody-an302056l
