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Antibodies

Recombinant GOLGA2/GM130 Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN302050L-50UL
100 ul
£402.00
AN302050L-100UL
About this Product
SKU:
AN302050L
Additional Names:
GOLGA;golgin A;GOLGA2;GM130;golgin A2;130 kDa cis Golgi matrix protein;130 kDa cis-Golgi matrix protein;Cis golgi matrix protein GM130;Gm130 autoantigen;GOGA2;GOLGA 2;Golgi autoantigen;Golgi autoantigen golgin subfamily a 2;Golgi matrix protein GM130;Golgin 95;Golgin subfamily a 2;Golgin subfamily A member 2;Golgin-95;MGC20672;SY11 protein
Application:
Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A770
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus,and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane. Required for normal protein transport from the endoplasmicreticulum to the Golgi apparatus and the cell membrane. Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at thecis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Golgidisassembly: phosphorylation at Ser-37 by CDK1 at the onset of mitosis inhibits the interaction with p115/USO1, preventing tethering of COPIvesicles and thereby inhibiting transport through the Golgi apparatus during mitosis. Also plays a key role in spindle pole assembly andcentrosome organization.
Host:
Rabbit
Immunogen:
Peptide. This information is proprietary to PTMab.
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies