Recombinant CEACAM6 Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN302030L-50UL
100 ul
£402.00
AN302030L-100UL
About this Product
- SKU:
- AN302030L
- Additional Names:
- CEACAM;CEACAM6;CD66c;CEAL;NCA;Carcinoembryonic antigen related cell adhesion molecule 6;Carcinoembryonic antigen related cell adhesion molecule 6 (non specific cross reacting antigen);Carcinoembryonic antigen-related cell adhesion molecule 6;CD 66c;CD66c antigen;CEA LIKE PROTEIN;CEACAM 6;CEAM6;MGC93832;Non specific cross reacting antigen;Non-specific crossreacting antigen;Normal cross reacting antigen;Normal cross-reacting antigen
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A750
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Carcinoembryonic antigen (CEA)-related cell adhesion molecule 6 (CEACAM6) is a member of the CEA-related cell adhesion molecule (CEACAM) family. CEACAMs bind to themselves and other family members to carry out numerous cellular functions, including proliferation, signaling, differentiation, tumor suppression, and survival. CEACAM6 is a single-chain, glycosylphosphatidylinositol (GPI)-anchored, highly glycosylated protein that is normally expressed on epithelial cells and granulocytes. CEACAM6 mediates homophilic and heterophilic cell adhesion with other CEA-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils, and plays a role in neutrophil adhesion to cytokine-activated endothelial cells. High levels of CEACAM6 expression are also observed in several different cancers. In cancer, CEACAM6 promotes tumor progression, migration, invasion, and metastasis, and therefore is considered a target for therapeutic intervention.
- Host:
- Rabbit
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_ceacam6_monoclonal_antibody-an302030l
