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Antibodies

Recombinant SPR Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN302028L-50UL
100 ul
£402.00
AN302028L-100UL
About this Product
SKU:
AN302028L
Additional Names:
SDR38C;member;OTTHUMP;SPR;SDR38C1;8 dihydrobiopterin:NADP+ oxidoreductase);member 1;OTTHUMP00000160199;Sepiapterin reductase;Sepiapterin reductase (7;Short chain dehydrogenase/reductase family 38C;SPRE
Application:
Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A748
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
SPR can catalyze the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.Defects in SPR are the cause of dystonia DOPA-responsive due to sepiapterin reductase deficiency (DRDSPRD). In the majority of cases, patients manifest progressive psychomotor retardation, dystonia and spasticity. Cognitive anomalies are also often present. The disease is due to severe dopamine and serotonin deficiencies in the central nervous system caused by a defect in BH4 synthesis.
Host:
Rabbit
Immunogen:
Peptide. This information is proprietary to PTMab.
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies