Recombinant Histone H3.3 Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN302024L-50UL
100 ul
£402.00
AN302024L-100UL
About this Product
- SKU:
- AN302024L
- Additional Names:
- H3F;histone H;H3F3A;H3.3A;H3F3;histone H3.3;family 3B (H3.3B);H3 histone;H3 histone family 3A;H3 histone family 3B;H3.3;H33;Histone H3.3Q;Histone H3.A;Histone H3.B;MGC87782;MGC87783;H3.3B;H3F3B;H3-3A;H3-3B;PP781
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A744
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Histone H3.3 is a histone H3 variant that replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
- Host:
- Rabbit
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_histone_h3.3_monoclonal_antibody-an302024l
