Recombinant Cadherin-6 Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN302008L-50UL
100 ul
£402.00
AN302008L-100UL
About this Product
- SKU:
- AN302008L
- Additional Names:
- CAD,Cadherin 6 type,CADH,CAD6,CADH6,Cadherin 6,Cadherin 6 type 2,Cadherin 6 type 2 K cadherin (fetal kidney),Cadherin fetal kidney,Cadherin6,Cadherin-6,CDH 6,KCAD,K-Cadherin,Kidney Cadherin,CDH6
- Application:
- Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A728
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Cadherin-6, also known as kidney cadherin (K-Cadherin, CDH6) is a type II classical cadherin. While it was reported to have a tumor suppressor function in cholangiocarcinoma, cadherin-6 expression was shown to be a marker of epithelial mesenchymal transition, and positively correlated with stage and metastasis of papillary thyroid carcinoma. In related studies, cadherin-6 was shown to interact with GABARAP and related proteins to restrain autophagy, thereby promoting metastatic behavior. Cadherin-6 has since been proposed as an antibody-drug conjugate target for the treatment of ovarian and renal cancers.
- Host:
- Rabbit
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_cadherin_6_monoclonal_antibody-an302008l
