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Antibodies

Recombinant CD137 Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN302006L-50UL
100 ul
£402.00
AN302006L-100UL
About this Product
SKU:
AN302006L
Additional Names:
TNFRSF;Cd137;Ila;Ly63;Tnfrsf9;4-1BB;TNFRSF9
Application:
Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A726
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
TNFRSF9 is a member of the tumor necrosis factor receptor superfamily. It is also called 4-1BB or CD137. 4-1BB/CD137/TNFRSF9 is expressed in activated CD4+ and CD8+ T cells, natural killer cells and dendritic cells. The ligand 4-1BBL/CD137L/TNFSF9 on antigen presenting cells binds to 4-1BB/CD137/TNFRSF9 and costimulates the activation of T cells. The binding of agonistic antibodies to 4 1BB/CD137/TNFRSF9 also leads to costimulation for T cell activation. Studies have shown the effectiveness of targeting 4 1BB/CD137/TNFRSF9 by its agonistic antibodies in cancer immunotherapy.
Host:
Rabbit
Immunogen:
Peptide. This information is proprietary to PTMab.
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies