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Antibodies

Recombinant Tissue Plasminogen Activator Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN302005L-50UL
100 ul
£402.00
AN302005L-100UL
About this Product
SKU:
AN302005L
Additional Names:
PLAT;T-PA;TPA;Tissue plasminogen activator;t-plasminogen activator;Alteplase;DKFZp686I03148;Plasminogen activator tissue;Plasminogen activator tissue type;Reteplase;t PA;T Plasminogen Activator;Tissue plasminogen activator (t PA);Tissue type plasminogen activator;Tissue-type plasminogen activator chain B;TPA1
Application:
Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A725
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Plasminogen activator, tissue (PLAT, synonyms: TPA, T-PA) is a tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein (33 kDa and 32 kDa). PLAT enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. tPA has 4 isoforms produced by alternative splicing with the MW of 63 kDa, 33 kDa, 57 kDa and 44 kDa.
Host:
Rabbit
Immunogen:
Peptide. This information is proprietary to PTMab.
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies