Recombinant CD8 beta Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN301982L-50UL
100 ul
£402.00
AN301982L-100UL
About this Product
- SKU:
- AN301982L
- Additional Names:
- LYT;LEU;CD8B;CD8B1;LEU2;LY3;LYT3;P37;T-Cell Surface Glycoprotein CD8 Beta Chain;CD8;Lyt3
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A702
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Cluster of Differentiation 8 (CD8) is a disulphide-linked heterodimer consisting of the unrelated A Alpha and B Beta subunits. Each subunit is a glycoprotein composed of a single extracellular Ig-like domain, a polypeptide linker, a transmembrane part and a short cytoplasmic tail. On T cells, CD8 is the coreceptor for the T cell receptor (TCR), and these two distinct structures recognize the Antigen-Major Histocompatibility Complex (MHC). Specifically, the Ig-like domain of CD8A Alpha interacts with the A Alpha3-domain of the MHC class I molecule. CD8 ensures specificity of the TCR-antigen interaction, prolongs the contact between the T cell and the antigen presenting cell, and the A Alpha chain recruits the tyrosine kinase Lck, which is essential for T cell activation.
- Host:
- Rabbit
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_cd8_beta_monoclonal_antibody-an301982l
