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Antibodies

Recombinant COUP-TFII Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301980L-50UL
100 ul
£402.00
AN301980L-100UL
About this Product
SKU:
AN301980L
Additional Names:
SVP;COT;CHTD;NF-E;COUP transcription factor;Apolipoprotein AI regulatory protein;Apolipoprotein A-I regulatory protein;Nuclear receptor subfamily 2 group F member;TFCOUP;COUP TF;COUP-TF;ARP;NR2F2;ARP1;CHTD4;COUPTFB;COUPTFII;NF-E3;SVP40;TFCOUP2;Apolipoprotein AI regulatory protein 1;Apolipoprotein A-I regulatory protein 1;ARP-1;COT2;COUP TF2;COUP transcription factor 2;COUP transcription factor II;COUP-TF II;COUP-TF2;NR2F1;Nuclear receptor subfamily 2 group F member 2
Application:
ChIP, Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A696
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Chicken ovalbumin upstream promoter transcription factor (COUP-TF) belongs to the NR2 subfamily of the nuclear hormone receptor family. COUP-TFI and COUP-TFII are two of the well-characterized members in the NR2 subfamily. These two members are highly conserved in their two zinc-finger DNA binding domains (DBD) and the ligand binding domain (LBD), and function as repressors or activators of downstream target genes to regulate different biological processes. COUP-TFI and II bind to 5'-AGGTCA-3' motif palindromes, either directly or indirectly, through heterodimer formation with other proteins (e.g. RXRs) to regulate downstream target gene expression. COUP-TFI is involved in neuronal development, tissue patterning, and differentiation. COUP-TFII has been shown to be involved in angiogenesis, glucose homeostasis, and mesenchymal cell commitment.
Host:
Rabbit
Immunogen:
Peptide. This information is proprietary to PTMab.
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies
Immunohistochemistry of paraffin-embedded Human testis using COUP-TFII Monoclonal Antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded Human breast cancer using COUP-TFII Monoclonal Antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded Mouse testis using COUP-TFII Monoclonal Antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded Rat testis using COUP-TFII Monoclonal Antibody at dilution of 1:100.
Chromatin immunoprecipitation analysis of MCF-7 immunoprecipitated DNA by real-time PCR using primers specific for the human TACSTD2-E, CYP24A1-E1, CYP24A1-E2, ZNF217-E1 and ZNF217-E2. The data are presented as enrichment of each sample relative to the total amount of input chromatin at each amplicon.