Recombinant Glutamate receptor 3 Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN301945L-50UL
100 ul
£402.00
AN301945L-100UL
About this Product
- SKU:
- AN301945L
- Additional Names:
- MRX;GRIA;GLUR;GluA;GLUR-K;GRIA3;GLUR-C;GLUR-K3;GLUR3;GLURC;GluA3;MRX94;AMPA 3;AMPA selective glutamate receptor 3;AMPA-selective glutamate receptor 3;dJ1171F9.1;GLUK3;GluR 3;GLUR C;GLUR K3;GluR-3;Glutamate ionotropic receptor AMPA type subunit 3;Glutamate receptor;Glutamate receptor 3;Glutamate receptor C;Glutamate receptor ionotrophic AMPA 3;Glutamate receptor ionotropic;Glutamate receptor subunit 3;GRIA 3;Ionotrophic Glutamate Receptor;ionotropic
- Application:
- Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A661
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4) that assemble as homo- or hetero-tetramers and mediate the majority of fast excitatory transmissions in the CNS. AMPARs are implicated in synapse formation, stabilization and plasticity. Glutamate receptor 3 (GluR3) knockout mice exhibited normal basal synaptic transmission and long-term depression (LTD) but enhanced long-term potentiation (LTP). In contrast, GluR 2/3 double knockout mice are impaired in basal synaptic transmission. Aberrant GluR3 expression or activity is implicated in a number of diseases, including autoimmune epilepsy, X-linked mental retardation, Rett's syndrome, amyotrophic lateral sclerosis and Alzheimer disease.
- Host:
- Rabbit
- Immunogen:
- Recombinant human Glutamate receptor 3 fragment
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_glutamate_receptor_3_monoclonal_antibody-an301945l
